Meta-analysis of dyspepsia and nonsteroidal antiinflammatory drugs

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Meta-analysis of dyspepsia and nonsteroidal antiinflammatory drugs.

OBJECTIVE Nonsteroidal antiinflammatory drug (NSAID) use is a known risk factor for gastrointestinal (GI) perforations, ulcers, and bleeds, but there are limited data on its association with the very common symptom of dyspepsia. Using published and unpublished data sources, we sought to determine estimates of the risks of dyspepsia associated with NSAIDs. METHODS We searched computerized data...

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Clinical trial data have prompted questions about the degree to which patients and their physicians should consider an increased risk of cardiovascular or cerebrovascular events when selecting medications for pain relief. Since the 2005 publication of a Science Advisory on the use of nonsteroidal antiinflammatory drugs (NSAIDs) by the American Heart Association,1 several important events have o...

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Nonsteroidal antiinflammatory drugs and bladder cancer: a pooled analysis.

Case-control studies have shown that regular use of nonsteroidal antiinflammatory drugs (NSAIDs) decreases bladder cancer risk, but few cohort studies have evaluated this association. The authors investigated NSAID use and bladder cancer in 3 large prospective studies (NIH-AARP Diet and Health Study; Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial; and U.S. Radiologic Technologist...

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ژورنال

عنوان ژورنال: Arthritis & Rheumatism

سال: 2003

ISSN: 0004-3591,1529-0131

DOI: 10.1002/art.11192